Publications

Tingan Zhou, Young-Kyoung Park, Jing Fu, Piotr Hapeta, Cinzia Klemm, Rodrigo Ledesma-Amaro (2025). Metabolic engineering of Yarrowia lipolytica for the production and secretion of the saffron ingredient crocetin. Biotechnology for Biofuels and Bioproducts 18 (1).

Harman Mehta, Jose Ignacio Jimenez, Rodrigo Ledesma-Amaro, Guy-Bart v Stan (2025). Investigating The Potential of Division of Labour in Synthetic Bacterial Communities for the Production of Violacein. bioRxiv.

Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2025). CRISPR/Cas13X-assisted programmable and multiplexed translation regulation for controlled biosynthesis. Nucleic Acids Research 53 (1).

Roberto Di Blasi, Jacopo Gabrielli, Kiyan Shabestary, Ioanna Ziarti, Tom Ellis, Cleo Kontoravdi, Rodrigo Ledesma-Amaro, Francesca Ceroni (2024). Understanding resource competition to achieve predictable synthetic gene expression in eukaryotes. Nature Reviews Bioengineering.

Mei-Li Sun, Ziyun Zou, Lu Lin, Rodrigo Ledesma-Amaro, Kaifeng Wang, Xiao-Jun Ji (2024). Systematic metabolic engineering of Yarrowia lipolytica for efficient production of phytohormone abscisic acid. Synthetic and Systems Biotechnology.

Wenchao Chen, Young-Kyoung Park, Lucie Studená, David Bell, Piotr Hapeta, Jing Fu, Peter J Nixon, Rodrigo Ledesma-Amaro (2024). Synthetic, marine, light-driven, autotroph-heterotroph co-culture system for sustainable β-caryophyllene production. Bioresource Technology 410.

Jing Fu, Simone Zaghen, Hongzhong Lu, Oliver Konzock, Naghmeh Poorinmohammad, Alexander Kornberg, Rodrigo Ledesma-Amaro, Deni Koseto, Alexander Wentzel, Francesca Di Bartolomeo, Eduard J Kerkhoven (2024). Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semipilot scale. Science Advances 10 (32).

Kiyan Shabestary, Cinzia Klemm, Benedict Carling, James Marshall, Juline Savigny, Marko Storch, Rodrigo Ledesma-Amaro (2024). Phenotypic heterogeneity follows a growth-viability tradeoff in response to amino acid identity. Nature Communications 15 (1).

Yaokang Wu, Yang Li, Yanfeng Liu, Xiang Xiu, Jiaheng Liu, Linpei Zhang, Jianghua Li, Guocheng Du, Xueqin Lv, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2024). Multiplexed in-situ mutagenesis driven by a dCas12a-based dual-function base editor. Nucleic Acids Research 52 (8).

Manman Sun, Alex Xiong Gao, Xiuxia Liu, Zhonghu Bai, Peng Wang, Rodrigo Ledesma-Amaro (2024). Microbial conversion of ethanol to high-value products: progress and challenges. Biotechnology for Biofuels and Bioproducts 17 (1).

Matthew J Pavlovich, Elena Borzova, Mao Mao, Zijie Meng, Jiankang He, Dichen Li, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, He Huang, Oliver Konzock, Jens Nielsen (2024). Introducing original research at Trends in Biotechnology. Trends in Biotechnology.

Manman Sun, Alex Xiong Gao, An Li, Rodrigo Ledesma‐Amaro, Peng Wang, Wenchao Chen, Zhonghu Bai, Xiuxia Liu (2024). Hyper‐production of porcine contagious pleuropneumonia subunit vaccine proteins in Escherichia coli by developing a bicistronic T7 expression system. Biotechnology Journal 19 (1).

Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, He Huang (2024). Harnessing oleaginous yeast to produce omega fatty acids. Trends in Biotechnology.

Haitao Hu, Wenbo Cheng, Xueyun Wang, Yu Yang, Xuemeng Yu, Jianwei Ding, Yiliang Lin, Wei Zhao, Qiao Zhao, Rodrigo Ledesma-Amaro, Xihan Chen, Junzhong Liu, Chen Yang, Xiang Gao (2024). Enhancing Plant Photosynthesis using Carbon Dots as Light Converter and Photosensitizer. bioRxiv.

Kaifeng Wang, Yueyue Zhou, Lizhen Cao, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2024). Engineering Yarrowia lipolytica for Sustainable Production of the Pomegranate Seed Oil-Derived Punicic Acid. Journal of Agricultural and Food Chemistry 72 (6).

Kaifeng Wang, Mingxue Yin, Mei-Li Sun, Quanyu Zhao, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, Lu Lin (2024). Engineering Yarrowia lipolytica for Efficient Synthesis of Geranylgeraniol. Journal of Agricultural and Food Chemistry.

Young-Kyoung Park, Huadong Peng, Piotr Hapeta, Lara Sellés Vidal, Rodrigo Ledesma-Amaro (2024). Engineered cross-feeding creates inter-and intra-species synthetic yeast communities with enhanced bioproduction. Nature Communications 15 (1).

Young-Kyoung Park, Lara Sellés Vidal, David Bell, Jure Zabret, Mladen Soldat, Martin Kavšček, Rodrigo Ledesma-Amaro (2024). Efficient synthesis of limonene production in Yarrowia lipolytica by combinatorial engineering strategies. Biotechnology for Biofuels and Bioproducts 17 (1).

Razieh Rafieenia, Cinzia Klemm, Piotr Hapeta, Jing Fu, María Gallego García, Rodrigo Ledesma-Amaro (2024). Designing synthetic microbial communities with the capacity to upcycle fermentation byproducts to increase production yields. Trends in Biotechnology.

Jorge Hernández-García, Antonio Serrano-Mislata, María Lozano-Quiles, Cristina Úrbez, María a Nohales, Noel Blanco-Touriñán, Huadong Peng, Rodrigo Ledesma-Amaro, Miguel a Blázquez (2024). DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants. Proceedings of the National Academy of Sciences 121 (19).

Wenwen Yu, Ke Jin, Dandan Wang, Nankai Wang, Yangyang Li, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2024). De novo engineering of programmable and multi-functional biomolecular condensates for controlled biosynthesis. Nature Communications 15 (1).

Mei-Li Sun, Yuting Han, Xiao Yu, Kaifeng Wang, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2024). Constructing a green oleaginous yeast cell factory for sustainable production of the plant-derived diterpenoid sclareol. Green Chemistry 26 (9).

Farshad Darvishi, Sajad Rafatiyan, Mohammad Hossein Abbaspour Motlagh Moghaddam, Eliza Atkinson, Rodrigo Ledesma-Amaro (2024). Applications of synthetic yeast consortia for the production of native and non-native chemicals. Critical Reviews in Biotechnology 44 (1).

Huadong Peng, Alexander PS Darlington, Eric J South, Hao-Hong Chen, Wei Jiang, Rodrigo Ledesma-Amaro (2024). A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities. Nature Microbiology 9 (3).

Young-Kyoung Park, Rodrigo Ledesma-Amaro (2023). What makes Yarrowia lipolytica well suited for industry?. Trends in Biotechnology 41 (2).

Ophelia S Venturelli, Harris H Wang, Sylvie Estrela, Kerwyn Casey Huang, Rodrigo Ledesma-Amaro, Alex JH Fedorec, Bärbel Stecher, Christopher E Lawson, Amir Zarrinpar, Chun-Jun Guo, Orkun S Soyer (2023). What is the key challenge in engineering microbiomes?. Cell Systems 14 (2).

Lucas Coppens, Tanya Tschirhart, Dagmar H Leary, Sophie M Colston, Jaimee R Compton, William Judson Hervey IV, Karl L Dana, Gary J Vora, Sergio Bordel, Rodrigo Ledesma‐Amaro (2023). Vibrio natriegens genome‐scale modeling reveals insights into halophilic adaptations and resource allocation. Molecular Systems Biology 19 (4).

Alicia E Graham, Rodrigo Ledesma-Amaro (2023). The microbial food revolution. Nature Communications 14 (1).

Javad Aminian-Dehkordi, Shadi Rahimi, Mehdi Golzar-Ahmadi, Amritpal Singh, Javiera Lopez, Rodrigo Ledesma-Amaro, Ivan Mijakovic (2023). Synthetic biology tools for environmental protection. Biotechnology Advances.

Young-Kyoung Park, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro (2023). Synthetic biology for producing value-added molecules in Yarrowia lipolytica. BioSynSys 2023.

Patrycja Szczepańska, Magdalena Rychlicka, Sylwia Groborz, Angelika Kruszyńska, Rodrigo Ledesma-Amaro, Andrzej Rapak, Anna Gliszczyńska, Zbigniew Lazar (2023). Studies on the Anticancer and Antioxidant Activities of Resveratrol and Long-Chain Fatty Acid Esters. International Journal of Molecular Sciences 24 (8).

Simran Kaur Aulakh, Lara Sellés Vidal, Eric J South, Huadong Peng, Sreejith Jayasree Varma, Lucia Herrera-Dominguez, Markus Ralser, Rodrigo Ledesma-Amaro (2023). Spontaneously established syntrophic yeast communities improve bioproduction. Nature Chemical Biology 19 (8).

Jinpeng Wang, Xiao Yu, Kaifeng Wang, Lu Lin, Hu-Hu Liu, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2023). Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids. Bioresource Technology 383.

Xianhao Xu, Xueqin Lv, Shixiu Cui, Yanfeng Liu, Hongzhi Xia, Jianghua Li, Guocheng Du, Zhaofeng Li, Rodrigo Ledesma-Amaro, Jian Chen, Long Liu (2023). Remodeling isoprene pyrophosphate metabolism for promoting terpenoids bioproduction. Engineering 28.

Ting Zhang, Qingdong Zeng, Fan Ji, Honghong Wu, Rodrigo Ledesma-Amaro, Qingshan Wei, Hao Yang, Xuhan Xia, Yao Ren, Keqing Mu, Qiang He, Zhensheng Kang, Ruijie Deng (2023). Precise in-field molecular diagnostics of crop diseases by smartphone-based mutation-resolved pathogenic RNA analysis. Nature Communications 14 (1).

Walid M El-Sharoud, Samar a Zalma, Leonardo Rios-Solis, Rodrigo Ledesma-Amaro (2023). Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox. Biotechnology Notes 4.

Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, He Huang (2023). Multienzymatic synthesis of nylon monomers from vegetable oils. Trends in Biotechnology 41 (2).

Huadong Peng, Ruiqi Chen, William M Shaw, Piotr Hapeta, Wei Jiang, David J Bell, Tom Ellis, Rodrigo Ledesma-Amaro (2023). Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast. ACS Synthetic Biology 12 (6).

Avinash Alagumalai, Balaji Devarajan, Hua Song, Somchai Wongwises, Rodrigo Ledesma-Amaro, Omid Mahian, Mikhail Sheremet, Eric Lichtfouse (2023). Machine learning in biohydrogen production: a review. Biofuel Research Journal 10 (2).

Xiuxia Liu, Manman Sun, Alex Xiong Gao, Rodrigo Ledesma-Amaro, Qiuwu Fang, Yankun Yang, Zhonghu Bai (2023). Leaderless Bicistronic Design for Precise and Reliable Control of Gene Expression in Corynebacterium Glutamicum. ACS Synthetic Biology 12 (7).

Kaifeng Wang, Wenyang Zhao, Lu Lin, Tianjing Wang, Ping Wei, Rodrigo Ledesma‐Amaro, Ai‐Hui Zhang, Xiao‐Jun Ji (2023). Inside Front Cover Image, Volume 120, Number 4, April 2023. Biotechnology and Bioengineering 120 (4).

Alice Boo, Harman Mehta, Rodrigo Ledesma-Amaro, Guy-Bart Stan (2023). Host-aware RNA-based control of synthetic microbial consortia. bioRxiv.

Li Sun, Quanwei Zhang, Xiao Kong, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Rodrigo Ledesma-Amaro, Jian Chen, Long Liu (2023). Highly efficient neutralizer-free l-malic acid production using engineered Saccharomyces cerevisiae. Bioresource Technology 370.

Manman Sun, Alex Xiong Gao, Xiuxia Liu, Yankun Yang, Rodrigo Ledesma-Amaro, Zhonghu Bai (2023). High-throughput process development from gene cloning to protein production. Microbial Cell Factories 22 (1).

Qian Cui, Yongjie Zhong, Wenkai Shang, Fuming Deng, Buhua Wang, Jiajia Wu, Peng Wang, Liudang Wan, Keling Wang, Lingchen Fang, Rui Dai, Han Zhang, Rodrigo Ledesma-Amaro, Yunuo Zhang, Jiaomei Huang (2023). Fluorescent Probe Combined with Photoelectric Analysis Technology for Detection of Escherichia coli. Biosensors 13 (2).

Alicia Climent-Catala, Ivan Casas-Rodrigo, Suhasini Iyer, Rodrigo Ledesma-Amaro, Thomas E Ouldridge (2023). Evaluating DFHBI-Responsive RNA Light-Up Aptamers as Fluorescent Reporters for Gene Expression. ACS Synthetic Biology 12 (12).

Xinyu Bi, Yang Cheng, Xianhao Xu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma‐Amaro, Long Liu (2023). etiBsu1209: A comprehensive multiscale metabolic model for Bacillus subtilis. Biotechnology and Bioengineering 120 (6).

Hyunbin Jin, Sojeong Kim, Daeyeol Lee, Rodrigo Ledesma-Amaro, Ji-Sook Hahn (2023). Efficient production of mycosporine-like amino acids, natural sunscreens, in Yarrowia lipolytica. Biotechnology for Biofuels and Bioproducts 16 (1).

Yaokang Wu, Yang Li, Ke Jin, Linpei Zhang, Jianghua Li, Yanfeng Liu, Guocheng Du, Xueqin Lv, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2023). CRISPR–dCas12a-mediated genetic circuit cascades for multiplexed pathway optimization. Nature Chemical Biology 19 (3).

Hao Yang, Rodrigo Ledesma-Amaro, Hong Gao, Yao Ren, Ruijie Deng (2023). CRISPR-based biosensors for pathogenic biosafety. Biosensors and Bioelectronics 228.

Wenjuan Li, Jie Mai, Lu Lin, Zhi‐Gang Zhang, Rodrigo Ledesma‐Amaro, Weiliang Dong, Xiao‐Jun Ji (2023). Cover Image, Volume 120, Number 12, December 2023. Biotechnology and Bioengineering 120 (12).

Kaifeng Wang, Lu Lin, Ping Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2023). Combining orthogonal plant and non-plant fatty acid biosynthesis pathways for efficient production of microbial oil enriched in nervonic acid in Yarrowia lipolytica. Bioresource Technology 378.

Wenjuan Li, Jie Mai, Lu Lin, Zhi‐Gang Zhang, Rodrigo Ledesma‐Amaro, Weiliang Dong, Xiao‐Jun Ji (2023). Combination of microbial and chemical synthesis for the sustainable production of β‐elemene, a promising plant‐extracted anticancer compound. Biotechnology and Bioengineering 120 (12).

Tao Sun, Yizi Yu, Lexin Wang, Yichun Qi, Tian Xu, Zhe Wang, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2023). Combination of a Push–Pull–Block Strategy with a Heterologous Xylose Assimilation Pathway toward Lipid Overproduction from Lignocellulose in Yarrowia lipolytica. ACS Synthetic Biology 12 (3).

Xueqin Lv, Shixiu Cui, Jie Chen, Lingrui Wang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xiaohao Liu, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2023). Cascaded de novo biosynthesis of lacto-proteins from CO 2 by engineered Pichia pastoris. Green Chemistry 25 (14).

Mei-Li Sun, Xiaoxia Gao, Lu Lin, Jing Yang, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2023). Building Yarrowia lipolytica Cell Factories for Advanced Biomanufacturing: Challenges and Solutions. Journal of Agricultural and Food Chemistry 72 (1).

M Walid, Samar a Zalma, Leonardo Rios-Solis, Rodrigo Ledesma-Amaro (2023). Biotechnology Notes. Biotechnology 4.

Jaroslav Hambalko, Peter Gajdoš, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro, Michal Tupec, Iva Pichová, Milan Čertík (2023). Biosynthesis of Fatty Acid Derivatives by Recombinant Yarrowia lipolytica Containing MsexD2 and MsexD3 Desaturase Genes from Manduca sexta. Journal of Fungi 9 (1).

Pei Liu, Yangmin Gong, Chen Yang, Rodrigo Ledesma-Amaro, Young-Kyoung Park, Shiyu Deng, Yuliang Wang, Hongbo Wei, Wenchao Chen (2023). Biorefining of rapeseed meal: A new and sustainable strategy for improving Cr (VI) biosorption on residual wastes from agricultural byproducts after phenolic extraction. Waste Management 165.

Scott Bottoms, Christina Mürk, Huadong Peng, Rodrigo Ledesma-Amaro, Mart Loog (2023). Bioconversion of Glucose-Rich Lignocellulosic Wood Hydrolysates to 3-Hydroxypropionic Acid and Succinic Acid using Engineered Saccharomyces cerevisiae. bioRxiv.

Laura E Walls, Peter Otoupal, Rodrigo Ledesma-Amaro, Sharon B Velasquez-Orta, John M Gladden, Leonardo Rios-Solis (2023). Bioconversion of cellulose into bisabolene using Ruminococcus flavefaciens and Rhodosporidium toruloides. Bioresource Technology 368.

William M Shaw, Lucie Studená, Kyler Roy, Piotr Hapeta, Nicholas S McCarty, Alicia E Graham, Tom Ellis, Rodrigo Ledesma-Amaro (2023). Author Correction: Inducible expression of large gRNA arrays for multiplexed CRISPRai applications. nature communications 14.

Kaifeng Wang, Wenyang Zhao, Lu Lin, Tianjing Wang, Ping Wei, Rodrigo Ledesma‐Amaro, Ai‐Hui Zhang, Xiao‐Jun Ji (2023). A robust soft sensor based on artificial neural network for monitoring microbial lipid fermentation processes using Yarrowia lipolytica. Biotechnology and Bioengineering 120 (4).

Lara Sellés Vidal, Mark Isalan, John T Heap, Rodrigo Ledesma-Amaro (2023). A primer to directed evolution: current methodologies and future directions. RSC Chemical Biology 4 (4).

Tigran v Yuzbashev, Evgeniya Y Yuzbasheva, Olga E Melkina, Davina Patel, Dmitrii Bubnov, Heiko Dietz, Rodrigo Ledesma-Amaro (2023). A DNA assembly toolkit to unlock the CRISPR/Cas9 potential for metabolic engineering. Communications Biology 6 (1).

C Geijer, R Ledesma-Amaro, E Tomás-Pejó (2022). Unraveling the potential of non-conventional yeasts in biotechnology. FEMS Yeast Research 22 (1).

Laura E Walls, Peter Otoupal, Rodrigo Ledesma-Amaro, Sharon B Velasquez-Orta, John M Gladden, Leonardo Rios-Solis (2022). Toward sustainable jet fuels: bioconversion of cellulose into isoprenoid biojet candidates using rumen bacteria and non-conventional yeast. BioRxiv.

Joshua M Lawrence, Yutong Yin, Paolo Bombelli, Alberto Scarampi, Marko Storch, Laura T Wey, Alicia Climent-Catala, PixCell IGEM Team, Geoff S Baldwin, Danny O’Hare, Christopher J Howe, Jenny Z Zhang, Thomas E Ouldridge, Rodrigo Ledesma-Amaro (2022). Synthetic biology and bioelectrochemical tools for electrogenetic system engineering. Science Advances 8 (18).

Eliza Atkinson, Zoltan Tuza, Giansimone Perrino, Guy-Bart Stan, Rodrigo Ledesma-Amaro (2022). Resource-aware whole-cell model of division of labour in a microbial consortium for complex-substrate degradation. Microbial cell factories 21 (1).

Yunhao Lu, Feng Li, Jinrong Bai, Rodrigo Ledesma-Amaro, Dayu Liu, Qiang He, Ruijie Deng (2022). Rapid screening of antimicrobial probiotics using CRISPR cascade. Biosensors and Bioelectronics 216.

Govindprasad Bhutada, Guillaume Menard, Rupam Kumar Bhunia, Piotr P Hapeta, Rodrigo Ledesma-Amaro, Peter J Eastmond (2022). Production of human milk fat substitute by engineered strains of Yarrowia lipolytica. Metabolic Engineering Communications 14.

Eliza Atkinson, Alice Boo, Huadong Peng, Guy‐Bart Stan, Rodrigo Ledesma‐Amaro (2022). Principles, Tools, and Applications of Synthetic Consortia Toward Microbiome Engineering. Principles in Microbiome Engineering.

Xueqin Lv, Angeles Hueso-Gil, Xinyu Bi, Yaokang Wu, Yanfeng Liu, Long Liu, Rodrigo Ledesma-Amaro (2022). New synthetic biology tools for metabolic control. Current Opinion in Biotechnology 76.

Xueqin Lv, Ke Jin, Guoyun Sun, Rodrigo Ledesma-Amaro, Long Liu (2022). Microscopy imaging of living cells in metabolic engineering. Trends in biotechnology 40 (6).

Yizi Yu, Yufan Zhou, Kaifeng Wang, Tao Sun, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2022). Metabolic and Process Engineering for Producing the Peach-Like Aroma Compound γ-Decalactone in Yarrowia lipolytica. Journal of Agricultural and Food Chemistry 71 (1).

William M Shaw, Lucie Studená, Kyler Roy, Piotr Hapeta, Nicholas S McCarty, Alicia E Graham, Tom Ellis, Rodrigo Ledesma-Amaro (2022). Inducible expression of large gRNA arrays for multiplexed CRISPRai applications. Nature Communications 13 (1).

Manman Sun, Alex Xiong Gao, Rodrigo Ledesma-Amaro, An Li, Rongbin Wang, Jianqi Nie, Pei Zheng, Yankun Yang, Zhonghu Bai, Xiuxia Liu (2022). Hypersecretion of OmlA antigen in Corynebacterium glutamicum through high-throughput based development process. Applied Microbiology and Biotechnology 106 (8).

Zhiqiang Wen, Zhenxiang Tu, Naief Al Makishah, Dahui Fang, Rodrigo Ledesma-Amaro, Jianguo Zhu, Qi Li, Yanan Li, Mingjie Jin (2022). Genetic Manipulation of a Twin Clostridia Consortium for Co-production of n-Butanol and Isobutanol by Consolidated Bioprocessing. ACS Sustainable Chemistry & Engineering 10 (45).

Kaifeng Wang, Tian-Qiong Shi, Lu Lin, Ping Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2022). Engineering Yarrowia lipolytica to Produce Tailored Chain-Length Fatty Acids and Their Derivatives. ACS synthetic biology 11 (8).

Lizhen Cao, Mingxue Yin, Tian-Qiong Shi, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2022). Engineering Yarrowia lipolytica to produce nutritional fatty acids: Current status and future perspectives. Synthetic and Systems Biotechnology 7 (4).

Kaifeng Wang, Tian-Qiong Shi, Jinpeng Wang, Ping Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2022). Engineering the Lipid and Fatty Acid Metabolism in Yarrowia lipolytica for Sustainable Production of High Oleic Oils. ACS Synthetic Biology 11 (4).

Valerie Ca Ward, Rodrigo Ledesma-Amaro (2022). Editorial overview: Chemical Biotechnology. Current opinion in biotechnology 75.

Razieh Rafieenia, Eliza Atkinson, Rodrigo Ledesma-Amaro (2022). Division of labor for substrate utilization in natural and synthetic microbial communities. Current Opinion in Biotechnology 75.

Nemailla Bonturi, Marina Julio Pinheiro, Paola Monteiro De Oliveira, Eka Rusadze, Tobias Eichinger, Gintare Liudžiūtė, Juliano Sabedotti De Biaggi, Age Brauer, Maido Remm, Everson Alves Miranda, Rodrigo Ledesma-Amaro, Petri-Jaan Lahtvee (2022). Development of a dedicated golden gate assembly platform (RtGGA) for Rhodotorula toruloides. Metabolic Engineering Communications 15.

Yameng Xu, Xinglong Wang, Chenyang Zhang, Xuan Zhou, Xianhao Xu, Luyao Han, Xueqin Lv, Yanfeng Liu, Song Liu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2022). De novo biosynthesis of rubusoside and rebaudiosides in engineered yeasts. Nature Communications 13 (1).

Yuxi Wang, Ting Xue, Minjin Wang, Rodrigo Ledesma-Amaro, Ying Lu, Xinyue Hu, Ting Zhang, Ming Yang, Yalun Li, Jin Xiang, Ruijie Deng, Binwu Ying, Weimin Li (2022). CRISPR-Cas13a cascade-based viral RNA assay for detecting SARS-CoV-2 and its mutations in clinical samples. Sensors and Actuators B: Chemical 362.

Meixi Ling, Yaokang Wu, Rongzhen Tian, Yanfeng Liu, Wenwen Yu, Guanjun Tao, Xueqin Lv, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2022). Combinatorial pathway engineering of Bacillus subtilis for production of structurally defined and homogeneous chitooligosaccharides. Metabolic Engineering 70.

Mei-Li Sun, Tian-Qiong Shi, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2022). Advancing Yarrowia lipolytica as a superior biomanufacturing platform by tuning gene expression using promoter engineering. Bioresource Technology 347.

Kaifeng Wang, Tian-Qiong Shi, Lu Lin, Ping Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, He Huang (2022). Advances in synthetic biology tools paving the way for the biomanufacturing of unusual fatty acids using the Yarrowia lipolytica chassis. Biotechnology Advances 59.

Wenjuan Li, Liuwei Cui, Jie Mai, Tian-Qiong Shi, Lu Lin, Zhi-Gang Zhang, Rodrigo Ledesma-Amaro, Weiliang Dong, Xiao-Jun Ji (2022). Advances in metabolic engineering paving the way for the efficient biosynthesis of terpenes in yeasts. Journal of Agricultural and Food Chemistry 70 (30).

Ran Lu, Tian-Qiong Shi, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji, He Huang (2022). Advances in metabolic engineering of yeasts for the production of fatty acid-derived hydrocarbon fuels. Green Chemical Engineering 3 (4).

Peter Gajdoš, Rodrigo Ledesma‐Amaro, Jean‐Marc Nicaud, Tristan Rossignol (2022). A yeast‐based tool for screening mammalian diacylglycerol acyltransferase inhibitors. MicrobiologyOpen 11 (6).

Peter Gajdoš, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud, Tristan Rossignol (2022). A yeast-based tool for mammalian DGATs inhibitors screening. bioRxiv.

Wenwen Yu, Ke Jin, Yaokang Wu, Quanwei Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Xueqin Lv, Rodrigo Ledesma-Amaro, Long Liu (2022). A pathway independent multi-modular ordered control system based on thermosensors and CRISPRi improves bioproduction in Bacillus subtilis. Nucleic Acids Research 50 (11).

Ting Zhang, Ruijie Deng, Yuxi Wang, Chengyong Wu, Kaixiang Zhang, Chunyan Wang, Ningqiang Gong, Rodrigo Ledesma-Amaro, Xucong Teng, Chunrong Yang, Ting Xue, Yong Zhang, Yun Hu, Qiang He, Weimin Li, Jinghong Li (2022). A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution. Nature Biomedical Engineering 6 (8).

Tengfei Niu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma‐Amaro, Long Liu (2021). The elucidation of phosphosugar stress response in Bacillus subtilis guides strain engineering for high N‐acetylglucosamine production. Biotechnology and Bioengineering 118 (1).

Farshad Darvishi, Mark Blenner, Rodrigo Ledesma-Amaro (2021). Synthetic Biology of Yeasts for the Production of Non-Native Chemicals. Frontiers in Bioengineering and Biotechnology 9.

Xueqin Lv, Yaokang Wu, Mengyue Gong, Jieying Deng, Yang Gu, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu, Jian Chen (2021). Synthetic biology for future food: research progress and future directions. Future Foods 3.

Chen Deng, Xueqin Lv, Jianghua Li, Hongzhi Zhang, Yanfeng Liu, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2021). Synergistic improvement of N-acetylglucosamine production by engineering transcription factors and balancing redox cofactors. Metabolic Engineering 67.

Bouchra Ezzamouri, Saeed Shoaie, Rodrigo Ledesma-Amaro (2021). Synergies of systems biology and synthetic biology in human microbiome studies. Frontiers in microbiology 12.

Lara Sellés Vidal, Rafael Ayala, Guy-Bart Stan, Rodrigo Ledesma-Amaro (2021). rfaRm: An R client-side interface to facilitate the analysis of the Rfam database of RNA families. Plos one 16 (1).

Weijian Wang, Xiao Yu, Yongjun Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2021). Reprogramming the metabolism of Klebsiella pneumoniae for efficient 1, 3-propanediol production. Chemical Engineering Science 236.

Alice Boo, Rodrigo Ledesma-Amaro, Guy-Bart Stan (2021). Quorum sensing in synthetic biology: A review. Current Opinion in Systems Biology 28.

Jaroslav Hambalko, Peter Gajdoš, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro, Michal Tupec, Iva Pichová, Milan Čertík (2021). Production of Long Chain Fatty Alcohols Found in Bumblebee Pheromones by Yarrowia lipolytica. Frontiers in Bioengineering and Biotechnology 8.

Mauricio Pesantes-Munoz, Rodrigo Ledesma-Amaro (2021). Pathway Engineering for Beta-Carotene and Carotenoid Biosynthesis in Y. lipolytica. Yarrowia lipolytica: Methods and Protocols.

Shixiu Cui, Xueqin Lv, Xianhao Xu, Taichi Chen, Hongzhi Zhang, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2021). Multilayer genetic circuits for dynamic regulation of metabolic pathways. ACS Synthetic Biology 10 (7).

Wei Jiang, David Hernández Villamor, Huadong Peng, Jian Chen, Long Liu, Victoria Haritos, Rodrigo Ledesma-Amaro (2021). Metabolic engineering strategies to enable microbial utilization of C1 feedstocks. Nature Chemical Biology 17 (8).

Wei Jiang, Huadong Peng, Rodrigo Ledesma-Amaro, Victoria S Haritos (2021). Metabolic Engineering of Yeast for Enhanced Natural and Exotic Fatty Acid Production. Emerging Technologies for Biorefineries.

Manman Sun, Xiong Gao, Rodrigo Ledesma-Amaro, An Li, Rongbing Wang, Jiangqi Nie, Pei Zheng, Yankun Yang (2021). Hypersecretion of vaccine antigen outer membrane lipoprotein A in Corynebacterium glutamicum through high-throughput based development process. Authorea Preprints.

Yongjun Wei, Boyang Ji, Rodrigo Ledesma-Amaro, Tao Chen, Xiao-Jun Ji (2021). Engineering yeast to produce plant natural products. Frontiers in Bioengineering and Biotechnology 9.

Tao Sun, Yizi Yu, Kaifeng Wang, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2021). Engineering Yarrowia lipolytica to produce fuels and chemicals from xylose: A review. Bioresource Technology 337.

Ran Lu, Lizhen Cao, Kaifeng Wang, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2021). Engineering Yarrowia lipolytica to produce advanced biofuels: Current status and perspectives. Bioresource Technology 341.

Evgeniya Y Yuzbasheva, Pasquale Scarcia, Tigran v Yuzbashev, Eugenia Messina, Iuliia M Kosikhina, Luigi Palmieri, Artem v Shutov, Maria O Taratynova, Rodrigo Ledesma-Amaro, Ferdinando Palmieri, Sergey P Sineoky, Gennaro Agrimi (2021). Engineering Yarrowia lipolytica for the selective and high-level production of isocitric acid through manipulation of mitochondrial dicarboxylate–tricarboxylate carriers. Metabolic Engineering 65.

Yirong Ma, Wenjuan Li, Jie Mai, Jinpeng Wang, Yongjun Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2021). Engineering Yarrowia lipolytica for sustainable production of the chamomile sesquiterpene (−)-α-bisabolol. Green Chemistry 23 (2).

Jie Mai, Wenjuan Li, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2021). Engineering plant sesquiterpene synthesis into yeasts: a review. Journal of Agricultural and Food Chemistry 69 (33).

Giansimone Perrino, Andreas Hadjimitsis, Rodrigo Ledesma-Amaro, Guy-Bart Stan (2021). Control engineering and synthetic biology: working in synergy for the analysis and control of microbial systems. Current Opinion in Microbiology 62.

Dingrong Kang, Saeed Shoaie, Samuel Jacquiod, Søren J Sørensen, Rodrigo Ledesma-Amaro (2021). Comparative Genomics Analysis of Keratin-Degrading Chryseobacterium Species Reveals Their Keratinolytic Potential for Secondary Metabolite Production. Microorganisms 9 (5).

Dingrong Kang, Saeed Shoaie, Samuel Jacquiod, Søren J Sørensen, Rodrigo Ledesma-Amaro (2021). Comparative genomics analysis of Chryseobacterium sp. KMC2 reveals metabolic pathways involved in keratinous utilization and natural product biosynthesis. bioRxiv.

Cuncui Kong, Zhuangzhuang Wang, Guanglei Liu, Zhenming Chi, Rodrigo Ledesma‐Amaro, Zhe Chi (2021). Bioproduction of L‐piperazic acid in gram scale using Aureobasidium melanogenum. Microbial Biotechnology 14 (4).

JM Lawrence, Y Yin, P Bombelli, A Scarampi, M Storch, LT Wey, A Climent-Catala, PixCell IGEM Team, GS Baldwin, D O’Hare, CJ Howe, JZ Zhang, TE Ouldridge, R Ledesma-Amaro (2021). A modular toolset for electrogenetics. bioRxiv.

Yanfeng Liu, Anqi Su, Jianghua Li, Rodrigo Ledesma-Amaro, Peng Xu, Guocheng Du, Long Liu (2020). Towards next-generation model microorganism chassis for biomanufacturing. Applied Microbiology and Biotechnology 104.

Zhiqiang Wen, Minrui Lu, Rodrigo Ledesma‐Amaro, Qi Li, Mingjie Jin, Sheng Yang (2020). TargeTron technology applicable in solventogenic clostridia: revisiting 12 years’ advances. Biotechnology Journal 15 (1).

Xueqin Lv, Yaokang Wu, Rongzhen Tian, Yang Gu, Yanfeng Liu, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2020). Synthetic metabolic channel by functional membrane microdomains for compartmentalized flux control. Metabolic engineering 59.

Rodrigo Ledesma-Amaro, Pablo I Nikel, Francesca Ceroni (2020). Synthetic biology-guided metabolic engineering. Frontiers in Bioengineering and Biotechnology 8.

Irene Hjorth Jacobsen, Rodrigo Ledesma-Amaro, José Luis Martinez (2020). Recombinant β-carotene production by Yarrowia lipolytica–assessing the potential of micro-scale fermentation analysis in cell factory design and bioreaction optimization. Frontiers in bioengineering and biotechnology 8.

Xianhao Xu, Xueliang Li, Yanfeng Liu, Yonglian Zhu, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2020). Pyruvate-responsive genetic circuits for dynamic control of central metabolism. Nature Chemical Biology 16 (11).

Nicholas S McCarty, Alicia E Graham, Lucie Studená, Rodrigo Ledesma-Amaro (2020). Multiplexed CRISPR technologies for gene editing and transcriptional regulation. Nature communications 11 (1).

Xiao-Jun Ji, Rodrigo Ledesma-Amaro (2020). Microbial lipid biotechnology to produce polyunsaturated fatty acids. Trends in biotechnology 38 (8).

Xianhao Xu, Yanfeng Liu, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2020). Microbial chassis development for natural product biosynthesis. Trends in biotechnology 38 (7).

Zhiqiang Wen, Rodrigo Ledesma-Amaro, Minrui Lu, Mingjie Jin, Sheng Yang (2020). Metabolic Engineering of Clostridium cellulovorans to Improve Butanol Production by Consolidated Bioprocessing. ACS synthetic biology 9 (2).

Jinpeng Wang, Rodrigo Ledesma-Amaro, Yongjun Wei, Boyang Ji, Xiao-Jun Ji (2020). Metabolic engineering for increased lipid accumulation in Yarrowia lipolytica–a review. Bioresource Technology 313.

Qingchun Ji, Jie Mai, Ying Ding, Yongjun Wei, Rodrigo Ledesma-Amaro, Xiao-Jun Ji (2020). Improving the homologous recombination efficiency of Yarrowia lipolytica by grafting heterologous component from Saccharomyces cerevisiae. Metabolic engineering communications 11.

Linlin Zhou, Zhiqiang Wen, Zedi Wang, Yuwei Zhang, Rodrigo Ledesma-Amaro, Mingjie Jin (2020). Evolutionary Engineering Improved d-Glucose/Xylose Cofermentation of Yarrowia lipolytica. Industrial & Engineering Chemistry Research 59 (39).

Amritpal Singh, Kenneth T Walker, Rodrigo Ledesma-Amaro, Tom Ellis (2020). Engineering bacterial cellulose by synthetic biology. International Journal of Molecular Sciences 21 (23).

Yaokang Wu, Taichi Chen, Yanfeng Liu, Rongzhen Tian, Xueqin Lv, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2020). Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis. Nucleic acids research 48 (2).

Qin He, Patrycja Szczepańska, Tigran Yuzbashev, Zbigniew Lazar, Rodrigo Ledesma-Amaro (2020). De novo production of resveratrol from glycerol by engineering different metabolic pathways in Yarrowia lipolytica. Metabolic engineering communications 11.

Young-Kyoung Park, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2020). De novo Biosynthesis of Odd-Chain Fatty Acids in Yarrowia lipolytica Enabled by Modular Pathway Engineering. Frontiers in bioengineering and biotechnology 7.

Zhiqiang Wen, Rodrigo Ledesma‐Amaro, Minrui Lu, Yu Jiang, Shuliang Gao, Mingjie Jin, Sheng Yang (2020). Combined evolutionary engineering and genetic manipulation improve low pH tolerance and butanol production in a synthetic microbial Clostridium community. Biotechnology and Bioengineering 117 (7).

Ashish a Prabhu, Dominic J Thomas, Rodrigo Ledesma-Amaro, Gary a Leeke, Angel Medina, Carol Verheecke-Vaessen, Frederic Coulon, Deepti Agrawal, Vinod Kumar (2020). Biovalorisation of crude glycerol and xylose into xylitol by oleaginous yeast Yarrowia lipolytica. Microbial cell factories 19.

Ashish a Prabhu, Rodrigo Ledesma-Amaro, Carol Sze Ki Lin, Frederic Coulon, Vijay Kumar Thakur, Vinod Kumar (2020). Bioproduction of succinic acid from xylose by engineered Yarrowia lipolytica without pH control. Biotechnology for biofuels 13.

Xueqin Lv, Cheng Zhang, Shixiu Cui, Xianhao Xu, Lingling Wang, Jianghua Li, Guocheng Du, Jian Chen, Rodrigo Ledesma-Amaro, Long Liu (2020). Assembly of pathway enzymes by engineering functional membrane microdomain components for improved N-acetylglucosamine synthesis in Bacillus subtilis. Metabolic Engineering 61.

Rachatida Det-Udom, Charlie Gilbert, Long Liu, Cheunjit Prakitchaiwattana, Tom Ellis, Rodrigo Ledesma-Amaro (2019). Towards semi-synthetic microbial communities: enhancing soy sauce fermentation properties in B. subtilis co-cultures. Microbial Cell Factories 18.

Suzie Hsu, Jay Huenemann, Vishwesh Kulkarni, Rodrigo Ledesma-Amaro, Robert Moseley, Nikita Mukhitov, Rashmi Tiwari, Shue Wang, Michael J Smanski (2019). The Five-Primer Challenge: An inquiry-based laboratory module for synthetic biology. bioRxiv.

Chen Deng, Xueqin Lv, Jianghua Li, Yanfeng Liu, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2019). Synthetic repetitive extragenic palindromic (REP) sequence as an efficient mRNA stabilizer for protein production and metabolic engineering in prokaryotic cells. Biotechnology and Bioengineering 116 (1).

Yang Gu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen, Ledesma-Amaro Rodrigo, Long Liu (2019). Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis. Metabolic engineering 51.

Nicholas S McCarty, Rodrigo Ledesma-Amaro (2019). Synthetic biology tools to engineer microbial communities for biotechnology. Trends in biotechnology 37 (2).

Rodrigo Ledesma-Amaro (2019). Synthetic biology and metabolic engineering in Yarrowia lipolytica: towards an affordable bioproduction. SIMB Annual Meeting and Exhibition 2019.

Sylwia Jezierska, Silke Claus, Rodrigo Ledesma-Amaro, Inge Van Bogaert (2019). Redirecting the lipid metabolism of the yeast Starmerella bombicola from glycolipid to fatty acid production. Journal of Industrial Microbiology and Biotechnology 46 (12).

Nicholas S McCarty, William M Shaw, Tom Ellis, Rodrigo Ledesma-Amaro (2019). Rapid Assembly of gRNA Arrays via Modular Cloning in Yeast. ACS synthetic biology 8 (4).

Alberto Jiménez, Gloria Muñoz‐Fernández, Rodrigo Ledesma‐Amaro, Rubén M Buey, José L Revuelta (2019). One‐vector CRISPR/Cas9 genome engineering of the industrial fungus Ashbya gossypii. Microbial biotechnology 12 (6).

Jean-Yves Trosset, Sami Tliba, Ali El Ati, Hela Friha, Estelle Mogensen, Jawher Kahouli, Robin Lacombe, Ouerdia Arkoun, Sette Diop, Rodrigo Ledesma-Amaro, Islam Boussaada (2019). Influence of micro-environment on yeast population dynamics. Ecological Engineering and Environment Protection 2019 (2).

Zhiqiang Wen, Rodrigo Ledesma-Amaro, Jianping Lin, Yu Jiang, Sheng Yang (2019). Improved n-Butanol Production from Clostridium cellulovorans by Integrated Metabolic and Evolutionary Engineering. Applied and environmental microbiology 85 (7).

Ewelina Celińska, Monika Borkowska, Wojciech Białas, Monika Kubiak, Paulina Korpys, Marta Archacka, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2019). Genetic engineering of Ehrlich pathway modulates production of higher alcohols in engineered Yarrowia lipolytica. FEMS yeast research 19 (2).

Shixiu Cui, Xueqin Lv, Yaokang Wu, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2019). Engineering a Bifunctional Phr60-Rap60-Spo0A Quorum-Sensing Molecular Switch for Dynamic Fine-Tuning of Menaquinone-7 Synthesis in Bacillus subtilis. ACS Synthetic Biology 8 (8).

Stefan Bruder, Eva Johanna Moldenhauer, Robert Denis Lemke, Rodrigo Ledesma-Amaro, Johannes Kabisch (2019). Drop-in biofuel production using fatty acid photodecarboxylase from Chlorella variabilis in the oleaginous yeast Yarrowia lipolytica. Biotechnology for biofuels 12.

Jieying Deng, Chunmei Chen, Yang Gu, Xueqin Lv, Yanfeng Liu, Jianghua Li, Rodrigo Ledesma-Amaro, Guocheng Du, Long Liu (2019). Creating an in vivo bifunctional gene expression circuit through an aptamer-based regulatory mechanism for dynamic metabolic engineering in Bacillus subtilis. Metabolic engineering 55.

Sylwia Jezierska, Silke Claus, Rodrigo Ledesma-Amaro, Inge Van Bogaert (2019). Converting the yeast Starmerella bombicola from a natural glycolipid producerto a free fatty acid production platform. SIMB Annual Meeting and Exhibition 2019.

Irene Hjorth Jacobsen, Rodrigo Ledesma-Amaro, José Luis Martinez Ruiz (2019). Assessing the potential of micro-fermentations through screening and media optimisation of recombinant β-carotene production by the yeast Yarrowia lipolytica.. 29th International Conference on Yeast Genetics and Molecular Biology.

Young-Kyoung Park, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro (2018). The engineering potential of Rhodosporidium toruloides as a workhorse for biotechnological applications. Trends in biotechnology 36 (3).

Macarena Larroudé, Tristan Rossignol, J-M Nicaud, Rodrigo Ledesma-Amaro (2018). Synthetic biology tools for engineering Yarrowia lipolytica. Biotechnology advances 36 (8).

Heber Gamboa-Melendez, Macarena Larroude, Young-Kyoung Park, Pauline Trebul, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro (2018). Synthetic biology to improve the production of lipases and esterases. Lipases and Phospholipases: Methods and Protocols.

Jingjing Liu, Jianghua Li, Yanfeng Liu, Hyun-Dong Shin, Rodrigo Ledesma-Amaro, Guocheng Du, Jian Chen, Long Liu (2018). Synergistic Rewiring of Carbon Metabolism and Redox Metabolism in Cytoplasm and Mitochondria of Aspergillus oryzae for Increased l-Malate Production. ACS Synthetic Biology 7 (9).

BA Blount, GO F Gowers, JCH Ho, R Ledesma-Amaro, D Jovicevic, RM McKiernan, ZX Xie, BZ Li, YJ Yuan, T Ellis (2018). Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome. Nature communications 9 (1).

Rodrigo Ledesma-Amaro, Alberto Jiménez, José Luis Revuelta (2018). Pathway Grafting for Polyunsaturated Fatty Acids Production in Ashbya gossypii through Golden Gate Rapid Assembly. ACS Synthetic Biology 7 (10).

Young-Kyoung Park, Thierry Dulermo, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2018). Optimization of odd chain fatty acid production by Yarrowia lipolytica. Biotechnology for biofuels 11.

Young-Kyoung Park, Thierry Dulermo, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2018). METABOLIC ENGINEERING OF YARROWIA LIPOLYTICA FOR PRODUCTION OF ODD CHAIN FATTY ACID. Non-Conventional Yeast Conference (NCYC).

José Luis Revuelta, Cristina Serrano-Amatriain, Rodrigo Ledesma-Amaro, Alberto Jiménez (2018). Formation of folates by microorganisms: towards the biotechnological production of this vitamin. Applied microbiology and biotechnology 102.

Xochitl Niehus, Anne-Marie Crutz-Le Coq, Georgina Sandoval, Jean-Marc Nicaud, Rodrigo Ledesma-Amaro (2018). Engineering Yarrowia lipolytica to enhance lipid production from lignocellulosic materials. Biotechnology for Biofuels 11.

Yaokang Wu, Taichi Chen, Yanfeng Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Rodrigo Ledesma-Amaro, Long Liu (2018). CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis. Metabolic engineering 49.

Macarena Larroude, Ewelina Celinska, Alexandre Back, Stephan Thomas, Jean‐Marc Nicaud, Rodrigo Ledesma‐Amaro (2018). A synthetic biology approach to transform Yarrowia lipolytica into a competitive biotechnological producer of β‐carotene. Biotechnology and bioengineering 115 (2).

Rémi Dulermo, François Brunel, Thierry Dulermo, Rodrigo Ledesma-Amaro, Jérémy Vion, Marion Trassaert, Stéphane Thomas, Jean-Marc Nicaud, Christophe Leplat (2017). Using a vector pool containing variable-strength promoters to optimize protein production in Yarrowia lipolytica. Microbial Cell Factories 16.

Govindprasad Bhutada, Martin Kavšček, Rodrigo Ledesma-Amaro, Stéphane Thomas, Gerald N Rechberger, Jean-Marc Nicaud, Klaus Natter (2017). Sugar versus fat: elimination of glycogen storage improves lipid accumulation in Yarrowia lipolytica. FEMS Yeast Research 17 (3).

Oleksiy O Lyzak, Rodrigo Ledesma-Amaro, Kostyantyn v Dmytruk, Andriy a Sibirny, Jose Luis Revuelta (2017). Molecular Studies of the Flavinogenic Fungus Ashbya gossypii and the Flavinogenic Yeast Candida famata. Biotechnology of yeasts and filamentous fungi.

Ewelina Celińska, Rodrigo Ledesma‐Amaro, Macarena Larroude, Tristan Rossignol, Cyrille Pauthenier, Jean‐Marc Nicaud (2017). Golden Gate Assembly system dedicated to complex pathway manipulation in Yarrowia lipolytica. Microbial Biotechnology 10 (2).

Patricia Lozano‐Martínez, Ruben M Buey, Rodrigo Ledesma‐Amaro, Alberto Jimenez, José Luis Revuelta (2017). Engineering Ashbya gossypii strains for de novo lipid production using industrial by‐products. Microbial Biotechnology 10 (2).

José Luis Revuelta, Rodrigo Ledesma-Amaro, Patricia Lozano-Martinez, David Díaz-Fernández, Rubén M Buey, Alberto Jiménez (2017). Bioproduction of riboflavin: a bright yellow history. Journal of Industrial Microbiology and Biotechnology 44 (4-5).

Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2016). Yarrowia lipolytica as a biotechnological chassis to produce usual and unusual fatty acids. Progress in lipid research 61.

Rémi Dulermo, Heber Gamboa-Meléndez, Rodrigo Ledesma‐Amaro, France Thevenieau, Jean-Marc Nicaud (2016). Yarrowia lipolytica AAL genes are involved in peroxisomal fatty acid activation. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids ….

Rodrigo Ledesma‐Amaro, Rubén M Buey, José Luis Revuelta (2016). The filamentous fungus Ashbya gossypii as a competitive industrial inosine producer. Biotechnology and Bioengineering 113 (9).

Rodrigo Ledesma-Amaro, Jose Luis Revuelta (2016). Synthetic biology and metabolic engineering to produce microbial oils: towards a sustainable source of fuels, chemicals and nutraceuticals. Bioenergy and bioremediation.

Alberto Jiménez, David Díaz-Fernández, Patricia Lozano-Martínez, Rodrigo Ledesma-Amaro, José Luis Revuelta (2016). Refactoring Ashbya gossypii for advanced biolipid production. New Biotechnology.

Peter Gajdoš, Rodrigo Ledesma-Amaro, Jean-Marc Nicaud, Milan Čertík, Tristan Rossignol (2016). Overexpression of diacylglycerol acyltransferase in Yarrowia lipolytica affects lipid body size, number and distribution. FEMS Yeast Research 16 (6).

Yasushi Kamisaka, Kazuyoshi Kimura, Hiroshi Uemura, Rodrigo Ledesma-Amaro (2016). Modulation of gluconeogenesis and lipid production in an engineered oleaginous Saccharomyces cerevisiae transformant. Applied Microbiology and Biotechnology 100.

Jose L Revuelta, Ruben M Buey, Rodrigo Ledesma‐Amaro, Erick J Vandamme (2016). Microbial biotechnology for the synthesis of (pro) vitamins, biopigments and antioxidants: challenges and opportunities. Microbial biotechnology 9 (5).

Rodrigo Ledesma-Amaro, Zbigniew Lazar, Magdalena Rakicka, Zhongpeng Guo, Florian Fouchard, Anne-Marie Crutz-Le Coq, Jean-Marc Nicaud (2016). Metabolic engineering of Yarrowia lipolytica to produce chemicals and fuels from xylose. Metabolic engineering 38.

Rodrigo Ledesma-Amaro, Jean-Marc Nicaud (2016). Metabolic engineering for expanding the substrate range of Yarrowia lipolytica. Trends in Biotechnology 34 (10).

José L Revuelta, Rodrigo Ledesma‐Amaro, Alberto Jiménez (2016). Industrial Production of Vitamin B2 by Microbial Fermentation. Industrial biotechnology of vitamins.

Cristina Serrano-Amatriain, Rodrigo Ledesma-Amaro, Rubén López-Nicolás, Gaspar Ros, Alberto Jiménez, José Luis Revuelta (2016). Folic acid production by engineered Ashbya gossypii. Metabolic engineering 38.

P Lozano-Martínez, R Ledesma-Amaro, JL Revuelta (2016). Engineering Ashbya gossypii for the production of ricinoleic and linoleic acid. Chem. Eng. Trans 49.

Rodrigo Ledesma-Amaro, Remi Dulermo, Xochitl Niehus, Jean-Marc Nicaud (2016). Combining metabolic engineering and process optimization to improve production and secretion of fatty acids. Metabolic engineering 38.

Remi Dulermo, Heber Gamboa-Meléndez, Rodrigo Ledesma-Amaro, France Thévenieau, Jean-Marc Nicaud (2015). Unraveling fatty acid transport and activation mechanisms in Yarrowia lipolytica. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids ….

Rodrigo Ledesma‐Amaro (2015). Microbial oils: a customizable feedstock through metabolic engineering. European Journal of Lipid Science and Technology 117 (2).

Rodrigo Ledesma-Amaro, Cristina Serrano-Amatriain, Alberto Jiménez, José Luis Revuelta (2015). Metabolic engineering of riboflavin production in Ashbya gossypii through pathway optimization. Microbial Cell Factories 14.

Rubén Martínez Buey, Rodrigo Ledesma-Amaro, Mónica Balsera, José M De Pereda, José Luis Revuelta Doval (2015). Increased riboflavin production by manipulation of inosine 5′-monophosphate dehydrogenase in Ashbya gossypii. Springer Nature.

Rubén M Buey, Rodrigo Ledesma-Amaro, Mónica Balsera, José María De Pereda, José Luis Revuelta (2015). Increased riboflavin production by manipulation of inosine 5′-monophosphate dehydrogenase in Ashbya gossypii. Applied microbiology and biotechnology 99 (22).

Rodrigo Ledesma-Amaro, Ruben M Buey, Jose Luis Revuelta (2015). Increased production of inosine and guanosine by means of metabolic engineering of the purine pathway in Ashbya gossypii. Microbial Cell Factories 14.

Rubén M Buey, Rodrigo Ledesma-Amaro, Adrián Velázquez-Campoy, Mónica Balsera, Mónica Chagoyen, José M De Pereda, José L Revuelta (2015). Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases. Nature communications 6 (1).

Rubén Martínez Buey, Rodrigo Ledesma-Amaro, Adrián Velázquez-Campoy, Mónica Balsera, Mónica Chagoyen, José M De Pereda, José Luis Revuelta Doval (2015). Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases. Nature Publishing Group.

Rodrigo Ledesma-Amaro, Thierry Dulermo, Jean-Marc Nicaud (2015). Engineering Yarrowia lipolytica to produce biodiesel from raw starch. Biotechnology for biofuels 8.

Rodrigo Ledesma-Amaro, Patricia Lozano-Martínez, Alberto Jiménez, José Luis Revuelta (2015). Engineering Ashbya gossypii for efficient biolipid production. Bioengineered 6 (2).

Rodrigo Ledesma‐Amaro, María‐Angeles Santos, Alberto Jiménez, José Luis Revuelta (2014). Tuning single‐cell oil production in Ashbya gossypii by engineering the elongation and desaturation systems. Biotechnology and bioengineering 111 (9).

Rodrigo Ledesma-Amaro (2014). Systems Metabolic Engineering in the industrial fungus Ashbya gossypii: boosting production of riboflavin, lipids and nucleosides. Systems Metabolic Engineering in the industrial fungus Ashbya gossypii ….

Rodrigo Ledesma-Amaro, María a Santos, Alberto Jiménez, José Luis Revuelta (2014). Strain design of Ashbya gossypii for single-cell oil production. Applied and Environmental Microbiology 80 (4).

Rodrigo Ledesma‐Amaro, Eduard J Kerkhoven, José Luis Revuelta, Jens Nielsen (2014). Genome scale metabolic modeling of the riboflavin overproducer Ashbya gossypii. Biotechnology and Bioengineering 111 (6).

R Ledesma-Amaro, MA Santos, A Jiménez, JL Revuelta (2013). Microbial production of vitamins. Microbial production of food ingredients.

Rodrigo Ledesma-Amaro, Alberto Jiménez, María a Santos, José L Revuelta (2013). Biotechnological production of feed nucleotides by microbial strain improvement. Process biochemistry 48 (9).